RSK4-IN-2
RSK4-IN-2 (compound 16o) is a potent orally active RSK4 inhibitor with an IC50 of 17 nM. It hinders the growth and invasion of esophageal squamous cell carcinoma (ESCC) cells by inhibiting the phosphorylation of RSK4 downstream targets. Additionally, RSK4-IN-2 impedes tumor growth and metastasis in a mouse model of ESCC, making it valuable for ESCC research.
Product Specifications
CAS Number
3034203-03-4
Smiles
O=C1C=NC=2C=NC (=NC2N1C3CCCC3) NC=4C=CC=5N=NNC5C4
Molecular Formula
C17H16N8O
Molecular Weight
348.37
Storage Conditions
-20°C
Notes
For research use only.
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