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C-Kit-IN-12

C-Kit-IN-12 (Compound 2a) is a potent c-Kit inhibitor with an IC50 of less than 10 nM across four KIT mutant cell models [BAF3 KIT EX11 DEL, EX11 DEL/D816H, EX11 DEL/T670I, EX11 DEL/V654A]. It is useful for research into c-Kit-associated diseases or disorders, such as cancer.

Product Specifications

CAS Number

2797973-68-1

Smiles

C (NC1=CC (C#CC=2SC (NC (=O) N3C[C@H] (O) CC3) =NC2) =C (C) C=C1) (=O) C4=CC (C (F) (F) F) =CC=N4

Molecular Formula

C24H20F3N5O3S

Molecular Weight

515.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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