Betamethasone succinate
Betamethasonesuccinate (NSSL-BMS) is a nanoformulation capable of crossing the blood-brain barrier, created by encapsulating Betamethasone hemisuccinate in PEGylated liposomes. By leveraging the enhanced permeability and retention effect of liposomes, Betamethasone succinate effectively delivers potent glucocorticoids to inflammatory sites. It inhibits the secretion of pro-inflammatory cytokines, such as TNF-α and IL-6, while maintaining the levels of the anti-inflammatory cytokine TGF-β. This compound is useful for researching arthritis and cerebral malaria.
Product Specifications
CAS Number
27297-42-3
Smiles
C[C@@]12[C@] ([C@]3 ([C@] (F) ([C@@H] (O) C1) [C@]4 (C) C (CC3) =CC (=O) C=C4) [H]) (C[C@H] (C) [C@@]2 (C (COC (CCC (O) =O) =O) =O) O) [H]
Molecular Formula
C26H33FO8
Molecular Weight
492.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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