VARS1-IN-1
VARS1-IN-1 is a valyl-tRNA synthetase (VARS1) inhibitor with a Kd value of 0.213 μM. It suppresses the aminoacylation activity of VARS1, decreases the charging level of valine tRNA, and reduces the overall protein synthesis rate. Additionally, VARS1-IN-1 inhibits the growth and cell proliferation of aggressive tumors in PC3 prostate cancer xenograft models, making it a valuable tool in prostate cancer research.
Product Specifications
CAS Number
428830-84-6
Smiles
O=C1N=C2SC (=NN2C (=N) C1=CC3=CNC=4C=CC=CC34) C=5C=CC (=CC5) C
Molecular Formula
C21H15N5OS
Molecular Weight
385.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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