EP055
EP055 is a non-hormonal male contraceptive agent. It targets the EPPIN protein on the surface of sperm, thereby inhibiting the binding of anti-EPPIN antibodies to EPPIN, with an IC50 value of 1121 μM. By reducing the internal pH and Ca2+ levels of sperm, EP055 induces sperm aggregation and inhibits sperm motility (IC50 value of 199.5 μM) . EP055 is applicable in the development of male contraceptives.
Product Specifications
CAS Number
2411173-40-3
Smiles
O=C (O) CSC=1N=C (N=C (N1) NC2=CC=C (NC (=O) C) C (O) =C2) NNC (=O) OC
Molecular Formula
C15H17N7O6S
Molecular Weight
423.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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