IRAK4-IN-34
IRAK4-IN-34 (compound 19) is a potent, highly selective, orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4), with an IC50 of 0.73 nM. It demonstrates excellent selectivity against hERG kinase and other kinases, possesses favorable in vivo pharmacokinetic properties, and is applicable for research in inflammatory diseases.
Product Specifications
CAS Number
2411498-83-2
Smiles
N (C=1C (=CN=C (C1) C=2N3C (=CC2) C=C (C#N) C=N3) C=4SC (=NN4) N5C[C@@]6 ([C@@H] (NC (C) =O) [C@] (C5) (CC6) [H]) [H]) C7 (C) COC7
Molecular Formula
C28H29N9O2S
Molecular Weight
555.66
Storage Conditions
-20°C
Notes
For research use only.
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