DB07006
DB07006 (compound 18) is a potent ATP-competitive dual inhibitor that targets Wee1 (IC50 = 0.030 μM) and Chk1 checkpoint kinase (IC50 = 0.018 μM) . In cellular models, DB07006 effectively blocks the G2/M checkpoint when used in combination with DNA-damaging agents. It holds potential applications in cancer research.
Product Specifications
CAS Number
622855-60-1
Smiles
O=C1NC (=O) C=2C1=C (C=C3C2C=4C=C (O) C=CC4N3CCCO) C=5C=CC=CC5OC
Molecular Formula
C24H20N2O5
Molecular Weight
416.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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