Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

KRAS G13D-IN-2

KRAS G13D-IN-2 (compound 8b) is a potent orally active inhibitor of KRAS G13D, with IC50 values of 1.95 μM in HCT-116G13D and 2.16 μM in HCT-15G13D. It induces G1 phase arrest and mitochondrial membrane depolarization. By inhibiting CDK6/TWIST1, KRAS G13D-IN-2 triggers cellular senescence. Additionally, it suppresses tumor growth in mouse models and is useful for studying KRAS G13D mutant colorectal cancer.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rat Kallikrein 4 (KLK4) ELISA Kit
EK15123 48 Tests

Rat Kallikrein 4 (KLK4) ELISA Kit

Sign In for Pricing
View Details
Anti-APOL3 antibody
STJ115781 100 µl

Anti-APOL3 antibody

Sign In for Pricing
View Details
1-tert-butyl-5-ethyl-1H-pyrazole-4-carboxylic acid
sc-339164 250 mg

1-tert-butyl-5-ethyl-1H-pyrazole-4-carboxylic acid

Sign In for Pricing
View Details
Whitlow/218 Linker (E3U7Q) Rabbit Monoclonal Antibody (Biotinylated)
CST 32523L 300 µL

Whitlow/218 Linker (E3U7Q) Rabbit Monoclonal Antibody (Biotinylated)

Sign In for Pricing
View Details
Edaradd sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K3780806 1.0 µg DNA

Edaradd sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

Sign In for Pricing
View Details
Ethyl 2,5-dibromo-1,3-oxazole-4-carboxylate
TRC-E915705-25MG 25 mg

Ethyl 2,5-dibromo-1,3-oxazole-4-carboxylate

Sign In for Pricing
View Details