RIPK1-IN-38
RIPK1-IN-38 is an orally active inhibitor of RIPK1 with an IC50 of 27 nM. It effectively suppresses the phosphorylation of RIPK1 and its downstream targets RIPK3 and MLKL. Demonstrating anti-necroptosis activity, RIPK1-IN-38 exhibits excellent anti-inflammatory properties in SIRS and GVHD models, making it suitable for research into inflammation and immune-related diseases.
Product Specifications
CAS Number
3092834-30-2
Smiles
C (N[C@@H] (C) C1=CC=C (F) C=C1) (=O) C2=C3N (N=C2) C=CC (=C3) C=4C=C5C (=CC4) N=C (NC (=O) C6CC6) S5
Molecular Formula
C27H22FN5O2S
Molecular Weight
499.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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