UK122 hydrochloride
UK122 hydrochloride is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA), with an IC50 of 0.2 μM. It shows little to no inhibitory effect on tissue-type PA (tPA), plasmin, thrombin, and trypsin (IC50 > 100 μM for all) . As a 4-oxazolidinone analog, UK122 hydrochloride acts as an anti-cancer agent by inhibiting cancer cell migration and invasion.
Product Specifications
Smiles
NC (c1ccc (/C=C2N=C (c3ccccc3) OC/2=O) cc1) =N.Cl
Molecular Formula
C17H14ClN3O2
Molecular Weight
327.76
Storage Conditions
-20°C
Notes
For research use only.
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