Valproic acid magnesium
Valproic acid magnesium (Magnesium valproate) is an orally active HDAC inhibitor with an IC50 ranging from 0.5 to 2 mM. It suppresses the activity of HDAC1 (IC50, 400 μM) and induces the degradation of HDAC2. Additionally, it activates Notch1 signaling and inhibits the proliferation of small cell lung cancer (SCLC) cells. Valproic acid magnesium is applicable in research on epilepsy, bipolar disorder, metabolic diseases, HIV infection, and migraines.
Product Specifications
CAS Number
62959-43-7
Smiles
O=C (C (CCC) CCC) [O-].O=C (C (CCC) CCC) [O-].[Mg+2]
Molecular Formula
C8H15O2.1/2Mg
Molecular Weight
155.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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