COX-2/5-LOX-IN-5

COX-2/5-LOX-IN-5 is an inhibitor targeting both COX-2 and 5-LOX, with IC50 values of 0.84 μM and 0.46 μM, respectively. This compound binds to the active sites of COX-2 and 5-LOX, effectively inhibiting inflammation mediated by prostaglandins and leukotrienes. COX-2/5-LOX-IN-5 is applicable in the study of inflammation.