Calcimycin hemicalcium hemimagnesium

Calcimycin (A-23187) hemicalcium hemimagnesium is an antibiotic and a unique divalent cation ionophore that facilitates the transport of ions such as calcium and magnesium. By increasing intracellular calcium levels, it triggers Ca2+-dependent cell death. Additionally, Calcimycin hemicalcium hemimagnesium inhibits the growth of Gram-positive bacteria and certain fungi, suppresses ATPase activity, uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, and induces apoptosis and autophagy.