Apoptosis inducer 53

Apoptosis inducer53 is an apoptosis inducer that inhibits the proliferation of human tumor cell lines (A549, HeLa, SW1573, T-47D, WiDr) with a GI50 value of 2.5-9.1 μM. It induces apoptosis in cancer cells and decreases colony formation. Furthermore, Apoptosis inducer53 activates the p38α MAPK signaling pathway and exhibits anti-inflammatory effects. It also shows activity against the protozoan parasite Leishmania donovani. Apoptosis inducer53 is applicable in research related to cancer, infections, and inflammation.