GTP-γ-S
GTPγS (Guanosine 5'-[γ-thio]triphosphate) acts as a G protein activator, protecting proteins from proteolytic degradation. It stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, enhances phospholipase activity, and induces actin polymerization. The combination of GTPγS and G protein α is useful for studying kinase activity. Additionally, GTPγS can be included as a component of lysis buffers.
Product Specifications
CAS Number
37589-80-3
Smiles
O[C@H]1[C@H] (N2C3=C (N=C2) C (=O) N=C (N) N3) O[C@H] (COP (OP (OP (=O) (O) S) (=O) O) (=O) O) [C@H]1O
Molecular Formula
C10H16N5O13P3S
Molecular Weight
539.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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