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SARS-CoV-2-IN-120

SARS-CoV-2-IN-120 (Compound S22) is a targeted inhibitor that prevents SARS-CoV-2 from entering cells. It binds to and accumulates within the cavity at the apex of the SARS-CoV-2 spike protein trimer, blocking the interaction between the RBD and ACE2. This compound is capable of neutralizing the BA.2 as well as subsequent Omicron variants and can suppress SARS-CoV-2 replication in mice.

Product Specifications

CAS Number

308293-08-5

Smiles

O=C (NC1=CC=C (C=C1) S (=O) (=O) NC2=NN=C (S2) CC) C3=CC=CC=4C=CC=CC43

Molecular Formula

C21H18N4O3S2

Molecular Weight

438.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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