SV119 hydrochloride
SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. It enhances the efficient transport of drugs across cancer cell membranes. Combining dm-Erastin with SV119 hydrochloride successfully overcomes internalization barriers observed in pancreatic cancer while retaining the inherent antitumor activity of Erastin. Additionally, SV119 hydrochloride exhibits cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis (apoptosis) .
Product Specifications
CAS Number
913816-12-3
Smiles
NCCCCCCN1[C@]2 ([H]) C[C@H] (C[C@@]1 ([H]) CCC2) OC (NC3=C (C=CC (C) =C3) OC) =O.Cl.Cl
Molecular Formula
C23H39Cl2N3O3
Molecular Weight
476.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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