β-carboline-ACS81

β-carboline-ACS81 is a potent antitumor β-carboline derivative. It induces apoptosis in HL-60 cells by causing mitochondrial membrane potential collapse and arrests the cell cycle at the G2/M phase. This compound exhibits significant antiproliferative activity against HL-60 cells (IC50 = 1.52 μM) . β-carboline-ACS81 is applicable for research in leukemia, histiocytic lymphoma, hepatocellular carcinoma, malignant melanoma, colorectal cancer, and lung cancer.