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EMC-AANL-DOX

EMC-AANL-DOX is a prodrug conjugate of Doxorubicin (DOX) activated by cysteine proteases. It exhibits antitumor activity in murine models of neuroblastoma (NB), breast cancer (4T1), fibrosarcoma (HT1080), and colorectal cancer liver metastases (CT26) . EMC-AANL-DOX is applicable for cancer research.

Product Specifications

CAS Number

1431625-66-9

Smiles

OC=1C2=C ([C@@H] (O[C@H]3C[C@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN4C (=O) C=CC4=O) =O) C) =O) C) =O) CC (N) =O) =O) CC (C) C) =O) [C@H] (O) [C@H] (C) O3) C[C@@] (C (CO) =O) (O) C2) C (O) =C5C1C (=O) C=6C (C5=O) =C (OC) C=CC6

Molecular Formula

C53H67N7O19

Molecular Weight

1106.15

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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