Lithocholic amide-C2-N (didecane)
Lithocholic amide-C2-N (didecane) (Compound LC10) is a derivative of lithocholic acid. This compound spontaneously forms lipid nanoparticles in aqueous environments, allowing it to penetrate the skin and reach the dermis, where it exerts anti-inflammatory effects on psoriasis-like chronic skin inflammation. Lithocholic amide-C2-N (didecane) inhibits abnormal keratinocyte proliferation, downregulates the mRNA expression of the psoriasis-related receptor EphA2, and reduces serum levels of various pro-inflammatory factors (such as IL-1α, IL-1β, and IFN-γ) by inhibiting the activation of the Th17/Th2 inflammatory pathways.
Product Specifications
CAS Number
2768690-22-6
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@H] (O) CC4) [H]) (CC1) [H]) [H]) (CC[C@@]2 ([C@@H] (CCC (NCCN (CCCCCCCCCC) CCCCCCCCCC) =O) C) [H]) [H]
Molecular Formula
C46H86N2O2
Molecular Weight
699.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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