PROTAC FSP1 degrader 1
PROTACFSP1 degrader 1 is an effective and selective PROTAC degrader that targets FSP1. It significantly induces the accumulation of lipid peroxides within cells. Additionally, PROTACFSP1 degrader 1 works synergistically with GPX4 inhibitors to enhance ferroptosis. It increases the mRNA expression of ferroptosis-related proteins (GPX4, FTH1, ACSL4, TfR1, FSP1) and is instrumental in the study of triple-negative breast cancer.
Product Specifications
CAS Number
3096510-51-6
Smiles
N#CC=1C2=NC=3C=CC=CC3N2C (NC (=O) CC (=O) NCCCCCNC4=CC=CC=5C (=O) N (C (=O) C45) C6C (=O) NC (=O) CC6) =C (C#N) C1C7=CC=C (C=C7) C
Molecular Formula
C41H35N9O6
Molecular Weight
749.79
Storage Conditions
-20°C
Notes
For research use only.
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