Antitumor agent-208
Antitumor agent-208, an analog of Bufalin, is a potent and orally active antitumor agent. It exhibits antiproliferative activity against tumor cell lines with an IC50 of 0.30-1.09 nM. In MV-4-11 xenograft mouse models, Antitumor agent-208 inhibits tumor growth. It is applicable in cancer research, including studies on acute myeloid leukemia (AML) and non-small cell lung cancer (NSCLC) .
Product Specifications
CAS Number
1385011-94-8
Smiles
O[C@@]12[C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@@H] (OC (NC5CCNCC5) =O) CC4) [H]) (CC[C@]1 (C) [C@H] (CC2) C=6C=CC (=O) OC6) [H]) [H]
Molecular Formula
C30H44N2O5
Molecular Weight
512.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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