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Antitumor agent-208

Antitumor agent-208, an analog of Bufalin, is a potent and orally active antitumor agent. It exhibits antiproliferative activity against tumor cell lines with an IC50 of 0.30-1.09 nM. In MV-4-11 xenograft mouse models, Antitumor agent-208 inhibits tumor growth. It is applicable in cancer research, including studies on acute myeloid leukemia (AML) and non-small cell lung cancer (NSCLC) .

Product Specifications

CAS Number

1385011-94-8

Smiles

O[C@@]12[C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@@H] (OC (NC5CCNCC5) =O) CC4) [H]) (CC[C@]1 (C) [C@H] (CC2) C=6C=CC (=O) OC6) [H]) [H]

Molecular Formula

C30H44N2O5

Molecular Weight

512.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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