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Picoberin

Picoberin is a potent inhibitor at low picomolar concentrations, effectively blocking osteoblast differentiation induced by the Hedgehog signaling pathway. As a strong aryl hydrocarbon receptor (AhR) agonist, it also inhibits Wnt3A-induced osteoblast differentiation in C3H10T1/2 cells. Additionally, Picoberin upregulates genes encoding phase I and II metabolic enzymes.

Product Specifications

CAS Number

3034663-23-2

Smiles

O=C1N2[C@] (C=3C (CC2) =CC=CC3) (CC=4C1=CC (Br) =C (Cl) C4) [H]

Molecular Formula

C17H13BrClNO

Molecular Weight

362.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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