Feniralstat hydrochloride
Feniralstat (compound 30) hydrochloride is a pyrazole derivative and an effective inhibitor of kallikrein, exhibiting an IC50 of 6.7 nM against human plasma kallikrein (pKal) . It shows no inhibitory effects on human KLK1, FXIa, or factor XIIa, with IC50 values exceeding 40 μM for each.
Product Specifications
CAS Number
2340299-00-3
Smiles
Cl.O=C1C=CC (F) =CN1CC2=CC=C (C=C2) CN3N=C (C (=C3) C (=O) NCC4=NC=CC (OC) =C4F) COC
Molecular Formula
C26H26ClF2N5O4
Molecular Weight
545.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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