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FXR agonist 14

FXR agonist14 (Compound V15) is a partial, selective, orally active FXR agonist with an EC50 of 0.67 nM. It can ameliorate the pathological features in mice with MASH induced by a high-fat, high-sugar diet, and shows significant effects against cholestatic liver disease.

Product Specifications

CAS Number

3062988-46-6

Smiles

O=C (OCC) C1CCN (C (=O) CC2=CC=C (C=C2) N (CC=3C=CC=C (F) C3) S (=O) (=O) C=4C=CC=CC4OC) CC1

Molecular Formula

C30H33FN2O6S

Molecular Weight

568.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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