Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PI3Kα-IN-29

PI3Kα-IN-29 is an efficacious, orally bioavailable, and selective PI3Kα inhibitor with an IC50 value of 2.5 nM. It demonstrates over 400-fold selectivity against PI3Kβ/δ/γ/mTOR. This compound selectively degrades the H1047R mutant p110α protein and inhibits PI3Kα kinase activity. PI3Kα-IN-29 suppresses the PI3K/AKT/mTOR signaling pathway, induces G1 phase arrest, and inhibits cell migration. Additionally, it impedes tumor growth in T47 mouse models and is applicable for breast cancer research.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), CF405S conjugate, 0.1mg/mL
BNC042452-100 1x 100 µL

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
SPATA22 (NM_001170698) Human Over-expression Lysate
LY432942 100 µg

SPATA22 (NM_001170698) Human Over-expression Lysate

Sign In for Pricing
View Details
SDHAF1 Mouse Monoclonal Antibody [Clone ID: OTI8C12]
CF809693 100 µg

SDHAF1 Mouse Monoclonal Antibody [Clone ID: OTI8C12]

Sign In for Pricing
View Details
Peripherin (PRPH) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7E4]
TA806226AM 100 µL

Peripherin (PRPH) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7E4]

Sign In for Pricing
View Details
Hydrazine Sulfate Salt
TRC-H718000-5G 5 g

Hydrazine Sulfate Salt

Sign In for Pricing
View Details
Frizzled 7 Rabbit Polyclonal Antibody
HA500433 100 µL

Frizzled 7 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details