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AZ1136

AZ1136 is a highly selective γ-secretase modulator (GSM) that reduces the levels of Aβ42 and Aβ40, with IC50 values of 990 and 1400 nM, respectively. It increases the levels of Aβ39 and Aβ37 without affecting Aβ38. AZ1136 is utilized in Alzheimer's disease research.

Product Specifications

CAS Number

1380508-60-0

Smiles

O=C1C2=CN=C (N=C2N (C) CC (C=3C=CC=CC3) N1C) OC=4C=CC (=CC4) C=5OC=NC5

Molecular Formula

C24H21N5O3

Molecular Weight

427.46

Storage Conditions

-20°C

Notes

For research use only.

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