AZ1136
AZ1136 is a highly selective γ-secretase modulator (GSM) that reduces the levels of Aβ42 and Aβ40, with IC50 values of 990 and 1400 nM, respectively. It increases the levels of Aβ39 and Aβ37 without affecting Aβ38. AZ1136 is utilized in Alzheimer's disease research.
Product Specifications
CAS Number
1380508-60-0
Smiles
O=C1C2=CN=C (N=C2N (C) CC (C=3C=CC=CC3) N1C) OC=4C=CC (=CC4) C=5OC=NC5
Molecular Formula
C24H21N5O3
Molecular Weight
427.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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