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VS3

VS3 is an inhibitor of the YAP-TEAD interaction. By directly binding to the TEAD4 Interface 3 (Kd = 6 μM), VS3 disrupts the interaction between YAP and TEAD. It exhibits antiproliferative activity against HT29, HCT116, and A2780 cells. VS3 is useful for studying colorectal adenocarcinoma and ovarian cancer.

Product Specifications

CAS Number

2576427-49-9

Smiles

O=C1N=C2NNC=C2C (C3=CC=C (OCC=4C=CC=CC4C) C (OC) =C3) C1

Molecular Formula

C21H21N3O3

Molecular Weight

363.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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