VS3
VS3 is an inhibitor of the YAP-TEAD interaction. By directly binding to the TEAD4 Interface 3 (Kd = 6 μM), VS3 disrupts the interaction between YAP and TEAD. It exhibits antiproliferative activity against HT29, HCT116, and A2780 cells. VS3 is useful for studying colorectal adenocarcinoma and ovarian cancer.
Product Specifications
CAS Number
2576427-49-9
Smiles
O=C1N=C2NNC=C2C (C3=CC=C (OCC=4C=CC=CC4C) C (OC) =C3) C1
Molecular Formula
C21H21N3O3
Molecular Weight
363.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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