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JYL-273 analog-1

JYL-273 analog-1 (Compound 28, Example 45) is a potent agonist of the transient receptor potential ion channel (TRP Channel) (TRPV1) with a Ki value of 10.8 nM. It exhibits analgesic activity in the PBQ-induced writhing test with an ED50 of 1.0 mg/kg and is applicable for pain relief research.

Product Specifications

CAS Number

289902-71-2

Smiles

O=C (OCC (CNC (=S) NCC1=CC=C (O) C (OC) =C1) CC2=CC=C (C=C2) C (C) (C) C) C (C) (C) C

Molecular Formula

C28H40N2O4S

Molecular Weight

500.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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