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CHF-6333 xinafoate

CHF-6333 xinafoate is a neutrophil elastase (NE) inhibitor with an IC50 of 0.21 nM and a KD of 0.16 nM. It exhibits activity against both human (IC50= 0.22 nM) and rat (IC50= 3.63 nM) proteases and also inhibits proteinase 3 with an IC50 of 22 nM. This compound is applicable in bronchiectasis (BE) research.

Product Specifications

CAS Number

3071964-44-5

Smiles

OC=1C2=C (C=CC1C ([O-]) =O) C=CC=C2.C (OC) (=O) C=1[C@H] (N2C (N (C1C) C3=CC (C (F) (F) F) =CC=C3) =NNC2=O) C4=C (CC[N+] (C) (C) C) C=C (C#N) C=C4

Molecular Formula

C38H35F3N6O6

Molecular Weight

728.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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