Ceritinib-platinum (IV) -4-phenylbutyrate

Ceritinib-platinum (IV) -4-phenylbutyrate (complex 7) is a Ceritinib-conjugated Platinum (IV) prodrug with anticancer properties. It can induce S phase arrest, DNA damage response, and apoptosis. In cancer cell models, Ceritinib-platinum (IV) -4-phenylbutyrate exhibits cytotoxicity, immune activation, and anti-invasion effects. This compound is applicable in cancer research, such as in non-small cell lung cancer (NSCLC) .