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TEAD-IN-23

TEAD-IN-23 (Compound 22) is a potent pan-TEAD inhibitor with an IC50 of 10 nM. It exhibits strong antiproliferative activity against NCI-H226 and MSTO-211H cell lines. In the MSTO-211H xenograft tumor model, TEAD-IN-23 causes complete tumor regression. This compound is suitable for research on mesothelioma and hepatocellular carcinoma.

Product Specifications

CAS Number

3074990-47-6

Smiles

FC (F) (F) C1=CC=C (OC2=CC (=CC (=C2) C) C3=CN (C=4C=CN=C (Cl) C34) CCO) C=C1

Molecular Formula

C23H18ClF3N2O2

Molecular Weight

446.85

Storage Conditions

-20°C

Notes

For research use only.

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