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JAK1/2-IN-3

JAK1/2-IN-3 is an inhibitor of both JAK1 and JAK2, demonstrating IC50 values of 14.73 nM and 10.03 nM, respectively. It can induce G2/M phase cell cycle arrest and trigger endogenous apoptosis (apoptosis) by increasing Bax and caspase3/7 levels while reducing Bcl2 expression. JAK1/2-IN-3 is applicable in research related to leukemia, breast cancer, and colon cancer.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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