(S) -Doxazosin

(S) -Doxazosin is a long-acting selective α1-adrenergic receptor antagonist. By selectively blocking postsynaptic α1 receptors, it reduces total peripheral resistance, thereby exerting an antihypertensive effect. (S) -Doxazosin lowers blood pressure in canine models of experimentally induced renal hypertension and alleviates bladder outflow obstruction. It is also applicable in research related to psychiatric disorders.