D2R/D3R/5-HT1AR agonist 1
D2R/D3R/5-HT1AR agonist 1 (compound 22b) is an orally active tri-target agonist with EC50 values of 1.29, 1.05, and 153.5 nM for D2R, D3R, and 5-HT1AR receptors, respectively. This compound improves MPTP-induced behavioral disorders and exhibits antidepressant properties, making it relevant for research in Parkinson's disease and depression.
Product Specifications
CAS Number
3028684-07-0
Smiles
N (CC1CCN (C (=O) N2CCOCC2) CC1) (CCC) [C@@H]3CC4=C (CC3) N=C (N) S4
Molecular Formula
C21H35N5O2S
Molecular Weight
421.6
Storage Conditions
-20°C
Notes
For research use only.
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