SALT629

SALT629 is an orally active antituberculosis agent with potent intracellular activity in macrophages (EC50 value of 1.5 μM) . It exhibits broad-spectrum activity against Mycobacterium tuberculosis (Mtb) across four different carbon sources, maintaining efficacy against drug-resistant strains and active against both slow-replicating and non-replicating Mtb. When combined with oxazolidinone drugs like Linezolid and Sutezolid, sALT629 shows synergistic activity. This compound is suitable for tuberculosis research.