MC-AcLys-GDEVD-PABC-Exatecan
MC-AcLys-GDEVD-PABC-Exatecan is a component of an antibody-drug conjugate (drug-linker conjugate for ADC) composed of an ADC linker (MC-AcLys-GDEVD-PABC) attached to the DNA topoisomerase I inhibitor, Exatecan. It operates by enhancing the release of small molecule drugs into the tumor microenvironment through a significant bystander effect, triggered by caspase-3-induced extracellular cleavage of the linker.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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