EGFR/InhA-IN-1

EGFR/InhA-IN-1 (Compound 15) is an inhibitor targeting the anticancer enzyme EGFR tyrosine kinase (1M17) with a Ki of 0.05 μM and the antituberculosis enzyme InhA (1OUZ) with a Ki of 0.02 μM. It exhibits antiproliferative activity against A549 cells (IC50 = 10.38 μM) and inhibits Mycobacterium tuberculosis H37Rv with a MIC of 6.25 μM. This compound can be utilized in studies related to non-small cell lung cancer and Mycobacterium tuberculosis infections.