α4β7 Integrin-IN-1
α4β7Integrin-IN-1 (Example 356) is a potent inhibitor of the α4β7 integrin, effectively blocking the interaction between α4β7 integrin and MadCAM-1 with an EC50 of 0.05 nM. This compound is utilized in research related to inflammatory bowel disease.
Product Specifications
CAS Number
2417307-52-7
Smiles
O=C1N (C=2C3=C (C (C[C@H] (NC (=O) C4=C (C) C=C (C=C4F) N5[C@@H] (C (F) (F) F) COCC5) C (O) =O) =CC2) C=CC=N3) C (=O) N (C) C=6C1=CC=NC6
Molecular Formula
C33H28F4N6O6
Molecular Weight
680.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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