Cbz-QFR-kbt
Cbz-QFR-kbt is a ketobenzothiazolone-based TMPRSS2 inhibitor with an IC50 of 0.42 nM. It also exhibits inhibitory activity against Matriptase, Hepsin, HGFA, and Factor Xa, with IC50 values of 1, 1.3, 85, and 85 nM, respectively. Furthermore, Cbz-QFR-kbt demonstrates significant inhibitory effects on SARS-CoV-2 and H1N1 (IC50= 60 nM) and is applicable for antiviral research.
Product Specifications
CAS Number
3086979-57-6
Smiles
C ([C@@H] (NC ([C@H] (CC1=CC=CC=C1) NC ([C@@H] (NC (OCC2=CC=CC=C2) =O) CCC (N) =O) =O) =O) CCCNC (=N) N) (=O) C3=NC=4C (S3) =CC=CC4
Molecular Formula
C35H40N8O6S
Molecular Weight
700.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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