Nampt-IN-10
Nampt-IN-10 (Compound 4) is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) . It exhibits nanomolar inhibitory activity against cell lines such as MDA-MB453, NCI-N87, and NCI-H526. Nampt-IN-10 can serve as an ADC payload, with ADCs constructed around it showing significant antitumor activity.
Product Specifications
CAS Number
2241015-68-7
Smiles
C (NC1=CC (F) =C (CNC (=O) C2=CC=C (C=C2) N3CCNCC3) C=C1) (=O) [C@@H]4[C@H] (C4) C=5C=CC=NC5
Molecular Formula
C27H28FN5O2
Molecular Weight
473.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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