AKT1-IN-11
AKT1-IN-11, a derivative of Podophyllotoxin, functions as a dual inhibitor of AKT1 and tubulin. It reduces phosphorylation levels of AKT kinase in tumor cells, disrupts cell proliferation, causes G2/M phase arrest, and induces apoptosis. Additionally, AKT1-IN-11 promotes tubulin depolymerization and is applicable in colorectal cancer research.
Product Specifications
CAS Number
3087064-94-3
Smiles
O=C1[C@@]2 ([C@@H] (C=3C ([C@H] (OCC4=CN (S (=O) (=O) C5=CC=C (NC (C) =O) C=C5) N=N4) [C@]2 (CO1) [H]) =CC6=C (C3) OCO6) C7=CC (OC) =C (OC) C (OC) =C7) [H]
Molecular Formula
C33H32N4O11S
Molecular Weight
692.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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