EEF1A2-IN-1

EEFA2-IN-1 is a potent covalent inhibitor of EEF1A2, exhibiting selective antiproliferative activity against osteosarcoma (OS) cells. It induces apoptosis by inhibiting EEF1A2 and downregulating the AKT signaling pathway. In xenograft mouse models, EEFA2-IN-1 suppresses tumor growth, making it a useful compound for osteosarcoma (OS) research.