TGFβ-IN-3
TGFβ-IN-3 (Compound 8) is a long-acting prodrug that acts as a TGFβR1 inhibitor with tumor-targeting activation. It enables selective drug release within tumors, offering a 2.2-fold increase in the tumor-to-blood ratio. TGFβ-IN-3 is applicable for colon cancer research.
Product Specifications
CAS Number
2857845-34-0
Smiles
C (COCNC (OCC1=CC=C (NC ([C@@H] (NC (CNC ([C@@H] (NC ([C@@H] (NC (COCCOCCNC (COCCOCCNC (CC[C@H] (NC (CCCCCCCCCCCCCCCCC (O) =O) =O) C (O) =O) =O) =O) =O) CC (C) C) =O) CO) =O) =O) CCCCN) =O) C=C1) =O) N2C (=C (N=C2) C3=CC (Cl) =C (F) C=C3) C4=NN5C (C=C4) =NC=C5C#N
Molecular Formula
C79H114ClFN16O20
Molecular Weight
1662.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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