Antibacterial agent 309

Antibacterialagent 309 (Compound C9) is an antibacterial agent that serves as a substrate for the AcrB efflux pump. It promotes the polymerization of FtsZ and exhibits antibacterial activity against erythromycin-resistant S. pyogenes2 (MIC = 0.25 μg/mL), penicillin-resistant S. aureusCI (MIC = 0.125 μg/mL), and penicillin-resistant S. epidermidis (MIC = 2 μg/mL) . However, it shows weak antibacterial activity against wild-type E. coli BW25113 (MIC = 256 μg/mL) .