EP4 receptor agonist 3 prodrug
EP4 receptor agonist 3 prodrug (Compound 9) serves as a prodrug for the EP4 receptor agonist (Compound 1a) . This prodrug exhibits no intrinsic agonistic activity at the EP4 receptor and requires specific hydrolysis by intestinal alkaline phosphatase (IAP) within the gut to release the active molecule, thereby exerting localized EP4 receptor activation. EP4 receptor agonist 3 prodrug demonstrates targeted action in the colon and significantly alleviates colitis symptoms in mice.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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