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CD28-IN-2

CD28-IN-2 is a selective inhibitor of the CD28-B7 interaction (IC50: 22.4 μM) that directly binds to CD28, with a Kd value of 24.1 μM. It inhibits CD28-driven immune activation and blocks T cell costimulation. CD28-IN-2 is applicable in the research of anti-tumor immunity and immune-related diseases.

Product Specifications

CAS Number

1240857-57-1

Smiles

O=C (OCC1=CC=C (C=C1) N2N=CC=C2) CC3=CC=C (OC) C (F) =C3

Molecular Formula

C19H17FN2O3

Molecular Weight

340.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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